I don't like to break the string for several reasons. For one, the connection in the pack between the series bricks is short, low resistance, and low inductance inside the pack, inside the cowl. There is no connector to "break" it with, and adding those connectors adds loss and inductance to the pack.
For another, it opens the potential for errors. Changing pack configurations can lead to errors which can damage wiring, connectors and cells, and even cause personal injury, fire or worse.
When I want to balance the three series "blocks" which are each 4P, I plug the balance charger into each section, one at a time. The balance charger I use charges through the balance leads so there is no "error" factor due to a second connector, or getting some sequence correct. It takes a little longer, but since I bulk charge first, and then balance charge, there is not much work left to do, so the balancing portion is very fast. The balance charger I use is the BC168 which can charge at up to 8 amps through the balance leads, however I generally limit it to 3 or 4 amps for each cell group in the 6S block, and this is enough current to balance very quickly. I have to plug it in 3 times, once for each block, but this is simple and foolproof. One connector. The blocks are already permanently paralleled, so there are three connectors on the bike, one for each group, and only one is used at a time. These same connectors are used to check balance, most of the time they are tucked under the cowl.
Simple is best. Balancing is rarely needed, I generally do it twice a year but it hasn't needed it that often. I can check it anytime, I generally use one of the little 6 cell battery medics to measure the cell groups every few days when I am using the bike.
That's the way I approach it. There are many ways to do it. My goal is to have a very solid pack that can deliver a lot of current to the controller with robust, short cables that minimize the impedance. Both resistance and inductance in the battery cabling is not good for the controller as it increases the voltage spikes on the FETs and ripple current in the controller's capacitor bank. This pack is 18S 32AH and can be asked to supply 80 amps continuous when climbing a big hill (2.5C). Between each Multistar brick and the controller are only 2 connectors and a couple feet total of dual 12 gauge wires in parallel, so about 9 gauge. That's from memory, it might be dual 10 gauge, but either way it is sweet and short. All the connections are hydraulically crimped into nearly solid masses of copper with multiple layers of heatshrink for a rugged system. The connectors are the XT's on the battery as they came, and the Anderson PP75 to the controller. Big and beefy. As far as I know, nothing gets warm. But making a path this low in resistance and inductance (all wires are paired to minimize inductance) makes it hard to parallel the blocks for charging, and there is really no need to.