I have a 52v and a 72v bike. I have also ridden the 72v bike with the 52v battery.
Pros:
The ride is more relaxed, like an electric car or hub motor bike, the times you shift becomes drastically less.
You can get away with thinner wires to reach the same power (watts), and you will have smaller losses, in the wires.
It is easier on your drivetrain if you are smart about it. Pick a higher voltage, let the RPM go high, and in turn the torque will stay low. Your bike will be more reliable. You might lose the ability to pedal along in some circumstances.
Cons:
Due to the higher rpm, you will have higher mechanical efficiency losses(generally around 200w at full speed). Better to keep your rpm around 20-40% while cruising and 40-70% when racing.
It becomes more dangerous to touch, as a fully charged 72v is 84v, and that will start to get ugly if you touch it.
You can't increase the volts forever as for example the insulation on the copper of your motor is finite.
I would always go with a +50% jump in voltage over a +50% jump in amps(same power). Higher voltage is blissful driving, less shifts, less stress on drivetrain, you can rev it out and let that motor scream! :lol: