I find with my weight, 375lbs plus the ebike, I can't go around corners too fast. With the tire pressure at the middle rating psi wise, the tube would end up flat. I always go for 26x2.00 or 1.90, but have done 2.10 but I try not to go 2.10, and I go for normal knobbies on the rear wheel w/motor.
On Friday, I got 2 flats. One brand new tube did not last but a short ride before it went flat. Obviously when your on the last tube, out n aboot then you triple check everything rather then a quick glance. Check inside of tire all the way around, check spoke threads arent poking out, check wheels rim edges and tire seat, check that its not pinched.
Have you tried Thorn Proof tubes?
You can use an old thorn proof tube for a custom tire liner.
I buy mine from Amazon as no one local has any in stock, thorns are not an issue here.
I know for motorcycles there are Ultra Heavy Duty tubes, that can be 6mm thick, while average HD are 4mm. Could be a reason to go heavier setup with mc tubes and tires. I will be doing that for my next ebike buildup, Northrock XC00 fat bike, from a 26" fat wheel which is the height of a 29'er wheel, but I am going to lace either a fat Leaf 1500W or fat MXUS 3kw into a 19" mc rim, using 6mm UHD tubes, and a mc tire with mtb like tread. A quick search will come up with solutions others have done. On this route, you can look at Treatlandtv's website for mc rims, spokes, tires and lots more.
https://www.electricbike.com/moped-rims-tires-hubmotors/
17" mc = 20 or 21" bicycle
19" mc = 24" bicycle
20" mc is an old size, hard to find and when you do find it, it is expensive. Equates to 26" bicycle I'd assume.
21" mc is probably close to a 27.5" bicycle size, again, I'd assume.