Most controllers have an LVC (low voltage cutoff). Some of them are programmable. Some of them you solder jumpers on the board inside. Some of them are automatic, and try to detect what nominal voltage your pack is whenever you connect it (but theyre not all good at it under all conditions). Some of them have no LVC. Youd have to find out how the LVC is implemented in any particular controller, or at least what its actual LVC value is, to know if its suitable for whatever battery you intend to use with it.
Just remember, without an actual cell-level BMS inside the battery (or some other cell-level monitoring), then you cant know if any cell group is going too high or too low during charge or discahrge. That means cells could be severely unbalanced, yet the pack still at the correct total voltage, such that some cells are so undercharged theyre damaged or destroyed by going to zero volts (or worse, negative voltage), and some cells are so overcharged they could catch fire. Its not all taht likely a scenario, but it does happen and it is why BMS are used. If cells always stayed balnced no one would need a BMS and no one would spend the money on making them.
With my EIG NMC cells, I dont use a BMS because they stay balanced. and discahrge and charge equally. under the usage I put them thru. WIth an 18650 pack I have, without the BMS in there it would probably get rapidly unbalanced and have problems, possibly severe ones.