I have only built half a dozen wheels, all with stainless 13g spokes, no problems so far. I would never use the radial pattern, if the rim didn't like the spoke angle of 1x I would replace the rim with something that would work at 1x. On a front wheel normally I would use 3x but I have just put a 17" moped rim on a front DH hub using 4x (only because I had some spokes the right length) and a Crystalyte rear hub motor, these rims are drilled at an angle for larger dia motorcycle hubs and worked great at 1x on the rear. Even with the optional larger dia nipples I used there was still enough clearance in the rims spoke holes to allow the angle I needed.
I also paid special attention to the spoke heads fit in the hub as this detail is important to help prevent spoke breakages!