You mean like biodiesel? The diesel engine was created to run on that, but the convenience of fossil fuel won out. Farmers used to make alcohol they could burn out of wastes on their land, burning some of it to distill the rest, but that becomes less and less convenient in society. If success is measured in convenience, it's not going to win out. But you can buy ready made systems to make biodiesel. They used to run trucks on gas vapors collected in a bladder on top, but so much trouble, eh? Worked just fine. When I was a kid I experimented with a pressure tank full of organics and a fire underneath, then it would run out of a line to a cooler catch tank and condense in there. I never really came up with a good engine to run on this pure alcohol, but I had my own lawnmower to play with and I could mix with gas, as was done during World War II. It's not as good as pure gas, so much for convenience.