To me anything higher than a pedelec type power ebike should use the largest practical wire gauge. When you skimp a shoot for the minimum wire gauge, then heat related failures in the wiring become pretty common around here. When you look at the maximum current listed on wire gauge charts like the one BigMoose shared or the one here
http://www.powerstream.com/Wire_Size.htm it becomes apparent why ES members have so many wire related failures. This is especially true once you consider that while a controller may be rated as say a 40A controller, that's on the battery side, but the phase wires can easily see 80-100A due to phase current multiplication that occurs with PWM.
The flip side of that is that our bikes move through the wind, so we typically have good air flow available to use to help keep wire temps down, so the max amps for chassis wiring or power transmission don't necessarily apply.