A pro pos, I suspect one of the big advantages with electric is that the engine is very massive (I guess at least 3-5 g/cm3?). So it should hopefully be possible to put this weight far forward and down.
The sweet spot is when there is no weight on the front nor the trailing wheel, but if this happens before you break traction, I suggest the center of mass is too high or too far back (compared to the ideal in theory). So I'm afraid hub motor is out, without even considering the loss of suspension performance.
LFP suggested that tires on F1 cars are able to pull 4-5g IIRC. Consider that the ground suddenly starts moving forward with an acceleration rate of 5g (5*9.81 m/s^2 - you'd spend 2.72 seconds to get to 300mph, in a vacuum). The center of mass (CM) has an equal force of 5g backwards, but it also has 1g force downwards. The pivot point (PP) is where the rear tyre touches the ground. If the tangens of the angle horizontal,PP,CM is less than 1/5 (11 deg), you can make a motor to drive such a tyre. But I guess it also has to be balanced so that you have enough traction to get the weight off of the front tyre to begin with. The farther back CM is on that 11 deg line, the more authority the rider would have over pitch angle. What is the wheelbase?
The required rear wheel torque turns out to be 8 400 NM so you might want to look at a bigger reduction than the 2.85 you mentioned.
With the 2.08 2nd gear ratio you'd be loafing at 6700rpm at 300mph - considering that the big piston engines can go past 15k it'd surprise me if it didn't make sense with a redline beyond 20k for a brushless electric? So then, with a 6:1 we're down to only 1400NM from the motor, unless you'd like the hassle with two gears.
If you cooled it to -196C (ln2) before start, the specific heat of copper would allow you to waste a continuous 27kw for each kg of copper for five seconds, then it would be at 150C. That's not taking into account any heat transfer. As a point of reference, 27kw for five seconds is enough to evaporate about 6cl of water.
I might be mistaken on all of this, haven't checked it very thoroughly. I use to find some zeroes misplaced or * where it should be / when I go over my math for the fifth time.
That red frame in the first post looks super flexy. But it looks easy to stiffen up once you have fitted the stuff you need on it. Is it possible that it is intended for the motor to be a stiffening part of the structure?