Right now many people still don't know E-bikes exist, so a good PR campaign including getting key celebrities to be seen on them is a start...
But other than that, the area I see lacking the most is in the bike frames available. I don't believe anyone can really compete on the variety or price of the various components, but frames are very lacking in the features I most want, and which I assume would prove to be very popular.
The existing frame that is closest to what I envision is the Electra Townie (shown above, roughly $600) for several reasons. I have an MTB, because it was the cheapest way to get fat tires, front suspension, and a front disc brake ($200). But I very much disliked the seating position, which I altered to be farther back and lower. But now the vehicle weight is too far back, I pop a wheelie when I hit a bump on an uphill.
The Townie has a longer frame, and I would elongate it another few inches to make room for an optional non-hub motor. Length added in the rear between the seat-post and the front of the rear tire, just above the standard kickstand-mounting (like the Z-bike battery in the post above).
The slanted seat-post means that as a shorter rider adjusts the seat closer to the pedals, they are also adjusting the seat closer to the ground. I like how my feet are now flat on the ground at a stop instead of on one toe.
Front suspension is optional on the Townie, but the long head tube means I might NOT be able to use commonly available front forks to cheaply make changes to the front forks, I must use an Electra fork. The head tube should be the type that pops-in a hundred different off-the-shelf forks.
Both fixed forks and suspension forks should have factory V-brake and ALSO disc brake mounting points (front and rear). An affordable base-model V-brake can then be upgraded to disc without having to buy an entire new fork (or involve welding).
Rear drop-outs and all fork options will be steel. The main frame "may" be aluminum.
As Miles has identified, a splined double ENO freewheel option on the right side of the rear hub would unleash a great deal of non-hub experimental improvements (resulting in upscale kits). By that I mean allowing a small RC motor to use three internal gears from a SRAM Dual-Drive would aid efficiency and hill-climbing heat. In this way a 750W "legal" E-bike would have greater range without increasing the battery size or expense, it would remain fairly light, and would have better top-speed and hill-climbing.
In short, the frame would have a comfortable riding position, large triangle to easily fit a central battery, and would have allowances for a front or rear hub, and would also allow the most popular non-hub configurations.