depends on the angles involved and the rim design, etc.
there's a lot of discussion about radial lacing, much of which is in the posts linked here. probably more than you want to read but it would help you understand the good and the bad
https://endless-sphere.com/forums/search.php?st=0&sk=t&sd=d&sr=posts&keywords=radial%2A+lac%2A-lack%2A
includes actual experience with such wheels over time for various users